Mast-MO (antibiotic wasp venom)

Source Web search
Organization University of Pennsylvania’s Perelman School of Medicine
Website URL www.pennmedicine.org/news/news-releases/2020/octobe…
Market status Early Stage Concept
Industry Medical
Value chain stage Input
Business models B2B + B2C
Product categories Medical Treatment
Biotech components Animal + Bacteria + Molecule
Organization type(s) University
Funding types University
Notes “The sting from a Korean yellow-jacket wasp doesn’t pose much of a danger to people—but it could be toxic enough to kill lethal bacteria that have become resistant to antibiotics. Now the insect has inspired scientists at the University of Pennsylvania’s Perelman School of Medicine to take a new approach to developing antibiotics...The team started with one ingredient in the wasp’s venom, a peptide called mastoparan-L (mast-L). This protein can kill bacteria, but it wouldn’t be safe for people at high doses. So the researchers engineered a version of the protein so that it targets E. coli while leaving healthy cells alone. They described the compound in the journal Proceedings of the National Academy of Sciences."
Added 4 years ago
Last modified 4 years ago